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ACTION
The method is called Skin Improve and has the function of optimizing skin physiology through fibroblastic
activation for the neo-formation of matrix components and for the normalization of the colloidal state of
the matrix, as well as to prevent damage from chronoaging caused by the free radicals.
The Medical Device used for this purpose contains:

• fragments of hyaluronic acid (20-38 monomers) capable of activating CD44 of fibroblast
• amino acid precursors for collagen, elastin and glycosaminoglycans
• antioxidants for the prevention of free radical damage
  The product should be administered intradermally according to the primary mesotherapy injecting
  technique.

PRINCIPLE OF METHOD
CD44 of the fibroblasts are activated and the cells in the surrounding area are provided with the necessary
principles for the build-up of collagen, elastin and glycosaminoglycans.
Biological optimization of skin condition will be obtained. In addition, acid buffering of the matrix maintains the
sol status of the colloidal solution and facilitates the metabolic exchanges. Eventually, the antioxidants block
the free radicals and allow the prevention of skin damages due to aging.
PRODUCT
Class III medical device with CE mark issued by the Istituto Superiore di Sanità and containing: fragments
of hyaluronic acid (20-38 monomers), amino acids, reduced glutathione, sodium ascorbyl phosphate,
phosphate – based buffer system.