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ACTION
Bio-restoration is performed through the activation of fibroblast subpopulation of fibrotic fibroblast in order to increase skin firmness with deposition of cicatrizing collagen (Type 1).
The Medical device used for this purpose contains:

• fragments of hyaluronic acid (20-30 monomers) capable of activating CD44 of fibroblasts
• acid and hypertonic solution able to induce an irritating reaction and stimulate fibrotic fibroblasts.
• amino acid precursors for collagen.
  Treatment should be performed on hypotonic tissues (face, neck, decolletté, buttock, thigh, arm, epigastric
  region)

PRINCIPLE OF METHOD
CD44 and CD40 of fibrotic fibroblasts are activated with fragments of hyaluronic acid and an acid and
hypertonic solution. Amino acids allow the formation of fibrotic collagen (Type 1).

PRODUCT
Class III medical device with CE mark issued by the Istituto Superiore di Sanità and containing: hyaluronic
acid and hyperosmolar solution of acidic pH.